In this conversation, Christina Dent and Stacey McKenna discuss the complexities of substance use, particularly in relation to motherhood and pregnancy. Stacey shares her personal journey with methamphetamine use and how it shaped her research as a medical anthropologist. They explore the impact of policies on substance use, the emotional context behind addiction, and the stigma surrounding mothers who use substances. The discussion emphasizes the importance of supportive environments and effective treatment options, particularly medications for opioid use disorder, to improve outcomes for both mothers and their children.